What is Cialis (drug name: Tadalafil)?
Cialis is in a class of medications known as PDE-5 inhibitors, and are used to treat cases of male impotence. Elli Lilly and Icos are currently marketing Cialis to the UK, Australia, New Zealand, and many other EU countries.
How well does
Cialis (tadalafil) work?
Cialis is approved in these markets for the treatment of mild to severe ED
(erectile dysfunction) at both the 10 and 20 mg doses. The labels in each of
these markets indicate that the product should be taken prior to anticipated
sexual activity without regard to food. Just like Viagra ®, sexual
stimulation is needed for Cialis to work. According to the European label,
the efficacy of Cialis may persist up to 24 hours after the pill is taken.
However, in Australia the label indicates efficacy up to 36 hours after
dosing.
How does
Cialis (tadalafil) work?
Cialis acts in the same way as Pfizer's Viagra ®, by blocking an enzyme
called phosphodiesterase-5, or PDE-5. This helps the smooth muscles in the
penis relax and widen, which allows for more blood to enter. As a result,
you gain erections faster and easier with Cialis.
Clinical Data Overview
Over 4,000 men have participated in more than 60 studies that clearly show
the safety and efficacy profile of Cialis. In primary efficacy studies
involving 1,112 men (804 Cialis, 308 placebo) with mild to severe ED, up to
81 percent of those treated with Cialis reported improved erections compared
with 35 percent of those taking placebo(1).
The most commonly reported adverse effects were headache, nasal congestion, backache, upset stomach, muscle ache, dizziness, and flushing. The adverse events reported with Cialis were transient and generally mild or moderate. As with other PDE5 inhibitors, the use of the drug, Cialis is contraindicated in patients who are taking nitrates. It should not be taken by patients with a few certain heart diseases for whom sexual activity itself is not advisable.
Remember that Cialis and, indeed, no medicine is for everyone. If you take any form of nitrates, often prescribed to control chest pains, please do not take Cialis. This combination could cause an unsafe drop in your blood pressure.
What's the normal Cialis (tadalafil) dose?
In Cialis clinical testing most men were administered one 10 mg Cialis or 20
mg Cialis tablet per day.
Are there any side effects with Cialis samples (tadalafil)?
The most common side effects reported with Cialis in the study were
headache, dyspepsia (upset stomach following meals), myalgia (muscle pain)
and back pain. The severities of these Cialis side effects were minimized
with lower doses of this prescription drug, Cialis.
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